What are the dissolution methods for hydroxypropyl methylcellulose (HPMC)?
Release Time:
Apr 15,2024
Mix HPMC powder with a large amount of other powdery substances, mix thoroughly with a mixer, and then add water to dissolve. At this time, HPMC can dissolve without clumping and agglomeration, because there is only a small amount of HPMC powder in every small corner, which will dissolve immediately when it comes into contact with water.
Hot water dissolution method: As HPMC does not dissolve in hot water, it can be uniformly dispersed in hot water in the initial stage, and then quickly dissolved during cooling. The two typical methods are described as follows:
1) Put the required amount of hot water into the container and heat it to approximately 70 ℃. Gradually add hydroxypropyl methyl cellulose with slow stirring, and HPMC begins to float on the surface of water, then gradually forms a slurry, which is cooled under stirring.
2) Add 1/3 or 2/3 of the required amount of water to the container, heat it to 70 ℃, disperse HPMC according to the method in 1), and prepare hot water slurry; Then add the remaining amount of cold water to the hot water slurry, stir and cool the mixture.
Powder mixing method: Mix HPMC powder with a large amount of other powdery substances, mix thoroughly with a mixer, and then add water to dissolve. At this time, HPMC can dissolve without clumping and agglomeration, because there is only a small amount of HPMC powder in every small corner, which will dissolve immediately when it comes into water—— Putty powder and mortar production enterprises are using this method. Hydroxypropyl methyl cellulose (HPMC) is used as a thickener and water retaining agent in putty powder mortar.
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